Danielle C. Morgan

Cryo-EM Structure of a Triazole alpha-Conotoxin GI Mimetic Bound to the Muscle-Type Nicotinic Acetylcholine Receptor

The paper designs and characterizes triazole-based peptidomimetics of the -GI conotoxin, showing they retain potency and provide structural insights into their interaction with the muscle-type nAChR.

The molecular mechanism of uptake and cell-to-cell transmission of arginine-containing dipeptide repeat proteins.

This paper identifies CSPG4 as a mediator of arginine-rich DPR uptake and cell-to-cell transmission, suggesting it as a therapeutic target for ALS/FTD.

Micromapping (μMap) of HER2 Across Human Breast Cancers: Photocatalytic Proximity Labeling Identifies Primary Resistance Mechanisms and Functional Interactors

The paper uses photocatalytic proximity labeling to map HER2 interactions in breast cancer, identifying galectins and PTPRF as key players in resistance and signaling.

Temporal Microenvironment Mapping (microMap) of Intracellular Trafficking Pathways of Cell-Penetrating Peptides Across the Blood-Brain Barrier

This paper introduces microMap, a nanoscale proximity labeling technique to map intracellular trafficking pathways of CPPs across the BBB using time-gated data.