Hitomi Watanabe

This study shows that 11β-HSD2 buffers maternal glucocorticoid surges during early development, preventing premature circadian clock activation and segmentation defects.

This study investigates the functional impact of pathogenic RHD mutations in Runx2 on skeletal and dental development in a mouse model of cleidocranial dysplasia.

The paper identifies a Ca2+-dependent sperm subpopulation that regulates embryo number in mammals by reducing fertilization rates when removed.

This study investigates how sclerostin modulates mineralization and stiffness in fibrocartilaginous entheses to maintain mechanical integrity.

This study shows that CLOCK/BMAL1 disrupts the segmentation clock in mouse embryonic organoids by interfering with Hes7 oscillation and transcriptional regulation.

This study shows that inhibiting N-myristoyltransferase (Nmt) promotes naive pluripotency in both mouse and human pluripotent stem cells.