Shinnosuke Higuchi

Divergent mechanics of inner ear morphogenesis are coupled to developmental tempo over vertebrate evolution

The paper examines inner ear morphogenesis across 12 vertebrate species, finding that divergent mechanical processes in tissue expansion are coordinated with developmental tempo to maintain conserved morphology.

Functional impact of pathogenic Runt domain mutations in Runx2 on skeletal and dental development in cleidocranial dysplasia

This study investigates the functional impact of pathogenic RHD mutations in Runx2 on skeletal and dental development in a mouse model of cleidocranial dysplasia.

Sclerostin modulates the degree of mineralization and the stiffness profile of the fibrocartilaginous enthesis for mechanical tissue integrity

This study investigates how sclerostin modulates mineralization and stiffness in fibrocartilaginous entheses to maintain mechanical integrity.