Dominique M. Missiakas

This study shows EzrA coordinates septal organization and nucleoid occlusion in S. aureus by spatially coupling peptidoglycan synthesis with surface protein display and preventing chromosome guillotining.

This study shows that orthogonal cell division in Staphylococcus aureus is essential for forming abscess communities by ensuring uniform adhesin distribution and fibrin capsule assembly.

This study identifies EssH as a cell wall hydrolase required for T7SSb-mediated protein secretion in S. aureus, revealing its role in facilitating secretion across the cell wall.

This study develops a polymer-lipid hybrid nanoparticle (PLNP) to enhance mRNA delivery and T cell immunity, showing improved antigen-specific T cell responses and protection against viral variants and cancer.

The paper develops dual-mode DARPin biologics that block both interfaces of ClfA, preventing S. aureus infections and offering protection against resistant strains.

This study evaluates monoclonal antibodies against ClfA to determine their ability to neutralize ClfA-ligand interactions and reduce S. aureus bacterial burdens in vivo.

The paper addresses statistical concerns about detecting natural selection during the Black Death using ancient genomic data, reaffirming findings related to immune loci and the ERAP2 variant.