Author

Sushim Kumar Gupta

Oklahoma State UniversityORCID 0000-0001-6520-6817Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Research Focus:drug response / drug discovery· 2 Assay:proteomics· 2 Organism:C. elegans· 1 Research Focus:cell type annotation· 1 Approach:deep learning· 1 Organism:E. coli· 1 Approach:experimental assay· 1 Research Focus:host-pathogen & immune response· 1

Frequent Co-Authors

Akhilesh RamachandraniD· 2 shared Joy ScariaiD· 2 shared Phurt HarnvoravongchaiiD· 2 shared Achuthan AmbatiD· 1 shared Alex Kidangathazhe· 1 shared Purna KashyapiD· 1 shared Ravi JadejaiD· 1 shared Shalabh Kumar MishraiD· 1 shared

Activity by Year

2024-2025 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 33 mutual co-author links

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2 shared papersMicrobiology

Akhilesh RamachandranORCID

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2 papers

Recent·Most cited

MicrobiologybioRxivPreprintDec 26, 2025

Rutin derived microbiota metabolite 3,4 dihydroxybenzoic acid restores antibiotic susceptibility in XDR Gram negative pathogens with a system wide susceptibility signature

Tanim Islam, Phurt Harnvoravongchai, Alex Kidangathazhe…·Joy Scaria

This study identifies 3,4-dihydroxybenzoic acid (DHBA), a rutin metabolite, as a potent antibiotic potentiator that restores susceptibility in XDR Gram-negative pathogens through a system-wide genetic susceptibility signature.

DOI 10.64898/2025.12.26.696599

E. coliproteomics

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MicrobiologybioRxivPreprintFeb 27, 2024

Caenorhabditis elegans model for in vivo screening of human gut microbiota mediated colonization and colonization resistance against Clostridioides difficile

Achuthan Ambat, Vishnu Thayil Valappil, Sudeep Ghimire…·Joy Scaria

This study uses C. elegans to screen human gut microbiota for colonization and resistance against C. difficile, finding 46% colonization success and 50% in vivo inhibition of C. difficile.

2 citations

C. elegansproteomics

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