Author

Di Chen

University of California, Los AngelesORCID 0000-0001-6546-3389Unclaimed ORCID profile · follow to get notified of new preprints

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Di Chen3 papers · Cornell University

Biology Disciplines

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Developmental Biology· 2

Signature Assays, Organisms & Methods

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Assay:bulk RNA-seq· 1 Research Focus:cell type annotation· 1 Research Focus:differential expression· 1 Approach:experimental assay· 1 Research Focus:gene regulatory network inference· 1 Organism:human· 1 Organism:rat· 1 Approach:statistical model· 1

Frequent Co-Authors

Amander T. ClarkiD· 2 shared Amanda J. CollieriD· 1 shared Bennett G. NovitchiD· 1 shared Enrique Sosa· 1 shared Ernesto J. RojasiD· 1 shared Felix Turcios· 1 shared Gunapala ShettyiD· 1 shared Heather R. ChristofkiD· 1 shared

Activity by Year

2018-2019 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 25 mutual co-author links

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2 shared papersDevelopmental Biology

Amander T. ClarkORCID

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2 papers

Recent·Most cited

Developmental BiologybioRxivPreprintDec 13, 2019

TGFβ superfamily signaling regulates the state of human stem cell pluripotency and competency to create telencephalic organoids

Momoko Watanabe, Jillian R. Haney, Neda Vishlaghi…·Bennett G. Novitch

This study shows that maintaining human pluripotent stem cells with feeders improves cortical organoid formation by activating TGFβ signaling and naive pluripotency genes, which can be mimicked with TGFβ growth factors.

8 citations

humanbulk RNA-seq

Developmental BiologyNature CommunicationsPeer-reviewedDec 11, 2018

Differentiation of primate primordial germ cell-like cells following transplantation into the adult gonadal niche

Enrique Sosa, Di Chen, Ernesto J. Rojas…·Amander T. Clark

This study validates the differentiation of rhesus macaque primordial germ cell-like cells (rPGCLCs) using transplantation into adult gonadal niches, showing they commit to late PGCs and spermatogonia-like cells but not ENO2-positive spermatogonia.

71 citations

ratexperimental assay