Giulia Amos

This study uses an in vitro platform to show that glioblastoma induces progressive reorganisation of neuronal networks, leading to altered network dynamics and reduced computational capacity.

This paper introduces a microfluidic platform to study neurodegeneration in human neural circuits, identifying early electrophysiological biomarkers of disease progression.

This paper introduces a water compartment cell culture lid that enables stable, long-term electrophysiological recordings of neuronal networks in vitro.

The paper develops an in vitro platform with biophysical modeling to study synaptic transmission in isolated human neuronal pairs, revealing receptor-specific changes in long-term potentiation.

This paper introduces human myelin spheres (MyS) as a model for studying myelination and demyelination, showing their ability to form myelinated neurons and mimic in vivo oligodendrocyte development.

MyeliMAP models human CNS myelination using hPSC-derived neurons and oligodendrocytes in a microfluidic platform, showing enhanced action potential conduction and stabilized network activity.

This study develops an in vitro retinothalamic nerve model using microfluidic channels to investigate signal transmission and network integrity.

This study investigates how microchannel width and spatial constraints affect axon growth in brain-on-chip systems, finding that restrictions smaller than 350nm prevent axon penetration.