Revathi Govind

This study identifies two naturally occurring CodY variants in C. difficile that alter ligand binding and virulence by affecting toxin repression and promoter binding.

This study develops a co-culture system to study C. difficile interaction with human intestinal epithelium and finds CCL20 expression is upregulated in response to the bacterium.

This study investigates glycogen metabolism's role in C. difficile virulence, finding that glycogen accumulation enhances spore resilience and disease relapse.

This study shows that Spo0A regulates the sin locus in C. difficile, controlling sporulation, toxin production, and motility by binding to its upstream region.