Jenni Kononoff

This study performs a GWAS on cocaine self-administration in rats, identifying six genome-wide significant loci, including one linked to carboxylesterase genes involved in cocaine metabolism.

The paper shows that escalation of cocaine intake, progressive ratio responding, and continued use despite adverse consequences are highly correlated in rats, with sex differences in addiction-like behaviors.

The paper identifies individual differences in oxycodone addiction-like behaviors in HS rats to uncover genetic factors contributing to vulnerability and resilience.

This study investigates the effects of deep brain stimulation (DBS) on cocaine self-administration in cocaine-dependent rats and finds it increases cocaine intake but raises GluR1 levels in the central nucleus of the amygdala.

This study examines irritability-like behavior in ethanol-dependent rats and shows that CRF1 receptor antagonism reduces this behavior during abstinence.

Cebranopadol reduces cocaine intake escalation and reinstatement in rats but induces conditioned place preference.