Author

Tobias Sjöblom

Uppsala UniversityORCID 0000-0001-6668-4140Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Bioinformatics· 1 Genetic & Genomic Medicine· 1 Genomics· 1

Signature Assays, Organisms & Methods

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Organism:human· 2 Assay:ATAC-seq· 1 Research Focus:benchmarking· 1 Approach:experimental assay· 1 Approach:statistical model· 1 Research Focus:variant calling· 1

Frequent Co-Authors

Anders IsakssoniD· 1 shared Anusha AmanullahiD· 1 shared Bengt GlimeliusiD· 1 shared Claire PallesiD· 1 shared Fredrik J. SwartlingiD· 1 shared Gabriela RoséniD· 1 shared Güler GüliD· 1 shared Hua ZhangiD· 1 shared

Activity by Year

2022-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 24 mutual co-author links

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1 shared paperGenetic & Genomic Medicine

Anders IsakssonORCID

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3 papers

Recent·Most cited

Genetic & Genomic MedicineGutPeer-reviewedSep 11, 2026

Heterozygous germline MSH3 mutations, and probably MLH3 mutations, act as classical tumour suppressors, leading to excess somatic deletion mutations, signature ID4 and increased colorectal cancer risk

Ignacio Soriano, Kitty Sherwood, Joseph C Ward…·Ian P.M. Tomlinson

DOI 10.1136/gutjnl-2026-338390

𝕏 PostBluesky

BioinformaticsCancersPeer-reviewedMar 15, 2023

Exact Probability Distribution for the ROC Area Under Curve

Joakim Ekström, Jim Ögren, Tobias Sjöblom

The paper derives the exact probability distribution for the ROC AUC-value, enabling precise statistical inference and demonstrates a geometric interpolation method to improve computational efficiency.

22 citations

statistical modelbenchmarking

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GenomicsGenome ResearchPeer-reviewedJan 1, 2022

Profiling chromatin accessibility in formalin-fixed paraffin-embedded samples

Hua Zhang, Vamsi Krishna Polavarapu, Pengwei Xing…·Xingqi Chen

This paper introduces FFPE-ATAC, a method for profiling chromatin accessibility in formalin-fixed paraffin-embedded tissues, demonstrating its effectiveness with colorectal cancer samples.

63 citations

𝕏 PostBluesky