Author

Helen Lindsay

Centre Hospitalier Universitaire Vaudois

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Bioinformatics· 2 Immunology· 2

Signature Assays, Organisms & Methods

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Research Focus:differential expression· 3 Approach:statistical model· 3 Research Focus:cell type annotation· 2 Research Focus:cell-cell communication· 2 Approach:experimental assay· 2 Organism:human· 2 Research Focus:variant effect prediction· 2 Approach:Bayesian inference· 1

Frequent Co-Authors

Constantinos PetrovasiD· 2 shared Fernanda Torres-RuiziD· 2 shared Laurence de LevaliD· 2 shared Mark D Robinson· 2 shared Michail OrfanakisiD· 2 shared Perla Mariana Del Rio EstradaiD· 2 shared Raphaël GottardoiD· 2 shared Spiros GeorgakisiD· 2 shared

Activity by Year

2014-2026 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 29 mutual co-author links

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2 shared papersImmunology

Constantinos PetrovasORCID

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Author profile →

4 papers

Recent·Most cited

An eicosanoid-enriched follicular microenvironment shapes germinal centre immune dynamics in antiretroviral-treated PLWH

Spiros Georgakis, Helen Lindsay, Michail Orfanakis, Jan Lukas Rinker, Perla M. Del Río Estrada, Riddhima Banga, Cloé Brenna, Senbai Kang, Fernanda Torres-Ruiz, Yara Andrea Luna-Villalobos, Gonzalo Salgado Montes de Oca, Matthieu Perreau, Mareva Delporte, Olivier Lambotte, Denarda Dangaj Laniti, , Constantinos Petrovas

The paper identifies eicosanoid-enriched follicular microenvironments in HIV-infected individuals on antiretroviral therapy that may influence antibody responses and viral reservoir persistence.

bioRxiv · Sep 14, 2026 · PreprintImmunology

Neutralization activity in chronic HIV infection is characterized by a distinct programming of follicular helper CD4 T cells

Eirini Moysi, Ashish A. Sharma, Sijy J. O'Dell, Spiros Georgakis, Perla Mariana Del Rio Estrada, Khader Ghneim, Alonso Arana, Fernanda Torres-Ruiz, Mauricio González-Navarro, Yara Andrea Luna-Villalobos, Santiago Ríos, Gustavo Reyes‐Terán, Margaret H. Beddall, Sung Hee Ko, Frida Belinky, , Constantinos Petrovas

The paper identifies distinct follicular helper CD4 T cell programming in HIV-positive individuals who produce broadly neutralizing antibodies, linking it to improved B cell follicle architecture and reduced suppressor cells.

Journal of Clinical Investigation · Jul 14, 2026Peer-reviewedImmunology

CrispRVariants: precisely charting the mutation spectrum in genome engineering experiments

Helen Lindsay, Alexa Burger, Berthin Biyong, Anastasia Felker, Christopher Hess, Jonas Zaugg, Elena Chiavacci, Carolin Anders, Martin Jinek, Christian Mosimann, Mark D Robinson

CrispRVariants provides a toolkit to accurately assess mutagenesis efficiency in genome editing experiments by analyzing sequencing data and resolving mutant alleles.

bioRxiv · Mar 10, 2016Bioinformatics

MINI REVIEW: Statistical methods for detecting differentially methylated loci and regions

Mark D Robinson, Abdullah Kahraman, Charity W Law, Helen Lindsay, Malgorzata Nowicka, Lukas M Weber, Xiaobei Zhou

This paper reviews statistical methods for detecting differentially methylated loci and regions, focusing on challenges like experimental design, false discovery control, and batch effects.

Frontiers in Genetics · Sep 16, 2014Peer-reviewedBioinformatics