Mikako Fujita

This study shows that inositol hexakisphosphate (IP6) is an essential cofactor for ADAR1 activity, with its depletion reducing RNA editing and supplementation restoring it.

This study reports the structure of the dimeric Keap1 Kelch domain at ambient temperature and identifies a novel compound, CNN, as a potential lead for Keap1 inhibition.

This paper identifies a heterocyclic compound, HT-7, that inhibits HIV-1 release by increasing cell surface BST2 expression with minimal cellular toxicity.

The paper presents the structure of TRAF6 N-terminal domain at 2.6 Å resolution, providing insights into its domain organization and zinc-binding, which are critical for its function and therapeutic targeting.