Author

Toshiaki Sawatani

Université Libre de BruxellesORCID 0000-0001-6714-6221Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

Click to filter author papers

Bioinformatics· 1 Genetics· 1 Molecular Biology· 1

Signature Assays, Organisms & Methods

Click to filter · or open tag

Research Focus:cell type annotation· 3 Research Focus:differential expression· 3 Research Focus:gene regulatory network inference· 3 Organism:human· 3 Approach:statistical model· 3 Assay:bulk RNA-seq· 2 Approach:experimental assay· 2 Assay:DNA methylation· 1

Frequent Co-Authors

Miriam CnopiD· 3 shared Ane Olazagoitia‐GarmendiaiD· 2 shared Cristina Moreno‐CastroiD· 2 shared María Nicol Arroyo· 2 shared Mariana Igoillo‐EsteveiD· 2 shared Adrian JaniszewskiiD· 1 shared Adrien RihouxiD· 1 shared Andréa Alex SchiavoiD· 1 shared

Activity by Year

2020-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 26 mutual co-author links

Click any collaborator node to inspect or filter shared papers

Focal author (center)Selected co-authorORCID co-authorUnlinked name

Curved chords = mutual co-authorship

3 shared papersMolecular Biology

Miriam CnopORCID

Mutual co-authors in cluster

Author profile →

3 papers

Recent·Most cited

Molecular BiologybioRxivPreprintJul 23, 2026

TRMT10A deficiency and tRNA fragmentation disrupt human pancreatic β-cell identity and insulin maturation

Cristina Moreno‐Castro, María Nicol Arroyo, Khadija Benabdallah…·Mariana Igoillo‐Esteve

This study shows TRMT10A deficiency causes β-cell dysfunction by promoting tRNA fragmentation and disrupting PCSK1 expression, leading to impaired insulin maturation and glucose-stimulated insulin secretion.

DOI 10.64898/2026.07.22.739528

humanbulk RNA-seq

𝕏 PostBluesky

GeneticsAdvanced SciencePeer-reviewedJun 29, 2023

The type 1 diabetes-associated lncRNA ARGI participates in virus-induced pancreatic beta cell inflammation.

Itziar González‐Moro, Koldo García‐Etxebarria, Luis Manuel Mendoza…·Izortze Santín

This study identifies the lncRNA ARGI as a mediator of virus-induced inflammation in pancreatic beta cells linked to type 1 diabetes through allele-specific transcriptional activation.

9 citations

humanDNA methylation

𝕏 PostBluesky

BioinformaticsbioRxivPreprintSep 23, 2020

Predicting the Key Regulators of Cell Identity in Human Adult Pancreas

Lotte Vanheer, Federica Fantuzzi, San Kit To…·Vincent Pasque

The paper reconstructs gene regulatory networks in human adult pancreatic cell types and identifies key transcription factors regulating cell identity.

4 citations

humanscRNA-seq

𝕏 PostBluesky