Author

San Kit To

Leuven Stem Cell InstituteORCID 0000-0002-3057-2902Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Developmental Biology· 2 Bioinformatics· 1

Signature Assays, Organisms & Methods

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Research Focus:cell type annotation· 3 Research Focus:differential expression· 2 Research Focus:gene regulatory network inference· 2 Organism:human· 2 Approach:statistical model· 2 Assay:bulk RNA-seq· 1 Approach:experimental assay· 1 Organism:mouse· 1

Frequent Co-Authors

Vincent PasqueiD· 3 shared Adrian JaniszewskiiD· 2 shared Joel ChappelliD· 2 shared Lotte VanheeriD· 2 shared Adrien RihouxiD· 1 shared Amitesh PandaiD· 1 shared Andréa Alex SchiavoiD· 1 shared Bradley Philip BalatoniD· 1 shared

Activity by Year

2019-2025 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 25 mutual co-author links

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3 shared papersDevelopmental Biology

Vincent PasqueORCID

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3 papers

Recent·Most cited

XIST Drives X-Chromosome Inactivation and Safeguards Female Extraembryonic Cells in Humans

Amitesh Panda, Leo Carrillo, Bradley Philip Balaton, Jeanne Brouillet, Solomon Nshemereirwe, Jarne Bonroy, Charbel Alfeghaly, Romina Facchinello, Sherif Khodeer, Ruben Boers, Gaël Castel, Charlie London, Emmanuel Cazottes, Madeleine Moscatelli, Raissa Songwa Tchinda, , Vincent Pasque

This study shows that XIST is required for XCI in human extraembryonic cells, which is essential for their survival and development.

bioRxiv · Nov 19, 2025 · PreprintDevelopmental Biology

Predicting the Key Regulators of Cell Identity in Human Adult Pancreas

Lotte Vanheer, Federica Fantuzzi, San Kit To, Andréa Alex Schiavo, Matthias Van Haele, Tine Haesen, Xiaoyan Yi, Adrian Janiszewski, Joel Chappell, Adrien Rihoux, Toshiaki Sawatani, Tania Roskams, François N. Pattou, Julie A. Kerr-Conte, Miriam Cnop, Vincent Pasque

The paper reconstructs gene regulatory networks in human adult pancreatic cell types and identifies key transcription factors regulating cell identity.

bioRxiv · Sep 23, 2020 · PreprintBioinformatics

Dynamic Erasure of Random X-Chromosome Inactivation during iPSC Reprogramming

Adrian Janiszewski, Irene Talón, Joel Chappell, Samuel Collombet, Juan Song, Natalie De Geest, San Kit To, Greet Bervoets, Oskar Marín-Béjar, Caterina Provenzano, Lotte Vanheer, Jean‐Christophe Marine, Florian Rambow, Vincent Pasque

This study investigates the dynamics of X-chromosome reactivation during mouse iPSC reprogramming, revealing hierarchical gene activation patterns and the role of chromatin regulators.

bioRxiv · Feb 9, 2019Developmental Biology