Minhwan Chung

The paper develops a DNA nanodevice to apply controlled forces to proteins, demonstrating its use in studying mechanosensitive protein interactions and identifying novel tension-dependent binders.

The paper develops a DNA-based molecular clamp to apply tension to proteins and study their interactions and structure under force.

This study identifies latrophilin-2 as an upstream mechanosensor for fluid shear stress in endothelial cells, linking it to vascular development and disease.

This study identifies latrophilins as essential for endothelial cell mechanotransduction of fluid shear stress through both G protein-dependent and -independent pathways.