Andrzej Antoni Szczepankiewicz

Arc/Arg3.1 binds the nuclear polyadenylate-binding protein RRM and regulates neuronal activity-dependent formation of nuclear speckles

This study identifies Arc/Arg3.1 as a regulator of PABPN1 nuclear speckles through direct binding, impacting mRNA processing during neuronal activity.

OMA1 protease eliminates arrested protein import intermediates upon depolarization of the inner mitochondrial membrane.

The paper identifies OMA1 protease as a key factor in resolving arrested protein import intermediates in human cells through mitochondrial membrane depolarization.

An important role of the interplay between Bdnf transcription and histone acetylation in epileptogenesis

The paper investigates the relationship between Bdnf transcription and histone acetylation in epilepsy, finding that Bdnf repositioning correlates with epileptic traits and is influenced by transcriptional activity and histone deacetylase inhibition.

Ultrastructural Visualization of 3D Chromatin Folding Using Serial Block-Face Scanning Electron Microscopy and In Situ Hybridization (3D-EMISH)

This paper develops a new electron microscopy method to visualize 3D chromatin folding at ultra-resolution in human cells and finds high heterogeneity in chromatin structures.