Andriy Goychuk

This study shows that IgD's long hinge increases entropic cost in antigen binding, reducing negative selection and raising the threshold for germinal center entry.

The paper investigates how active RNA synthesis influences nuclear condensate patterning by studying nucleolar fibrillar centers and shows that RNA synthesis affects their size, number, and spacing.

The paper develops a mathematical model to study how immune responses and metabolic pathway adaptations interact during infection, finding that glucose redistribution and cytokine regulation are critical for effective pathogen clearance.

The paper investigates how RNA gradients influence protein condensate motion toward promoters, showing implications for enhancer-promoter contacts and condensate-promoter interactions.