Age-associated modulation of TREM1/2- expressing macrophages promotes melanoma progression and metastasis
Marzia Scortegagna, Rabi Murad, Parinaz Bina…·Ze’ev A. Ronai
This study shows that aging alters macrophage phenotypes in the melanoma microenvironment, with TREM1 and TREM2 playing distinct roles in tumor progression and metastasis in aged mice.