Alex Rosa Campos

This study identifies PTX3 as a key antifibrotic factor secreted by fibroblasts that modulates epithelial repair in acute injury and exacerbates damage in chronic injury.

This study shows that increasing SORLA levels in aged tauopathy mice reduces multiple pathological effects, including tau phosphorylation, inflammation, and synaptic dysfunction.

The paper discovers a VHL molecular glue degrader of GEMIN3 using Picowell RNA-seq screening, showing how it targets GEMIN3 for degradation through ternary complex formation.

This study quantitatively analyzes plasma proteome changes in vaccinated individuals using a nanoparticle-based proteomic workflow, identifying proteins associated with vaccine response and COVID-19 infection.

The paper introduces secCellFie, a tool that infers secretory and metabolic pathway activity from omic data, demonstrating its application in immune cells, NAFLD hepatokine secretion, and antibody production in Chinese Hamster Ovary cells.

This study maps the SARS-CoV-2 virus-host interactome using BioID in A549 cells and provides a public resource for analyzing host-viral protein associations.

The 73-amino-acid SARS-CoV-2 membrane-associated protein ORF9c suppresses interferon, antigen presentation, and complement pathways while inducing IL-6 signaling in lung epithelial cells, an effect blunted by proteasome or VCP inhibition.