Author

Alessandro Datti

Lunenfeld-Tanenbaum Research InstituteORCID 0000-0001-6824-7382Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Biochemistry· 1 Systems Biology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Research Focus:drug response / drug discovery· 1 Organism:human· 1 Research Focus:protein design· 1 Research Focus:protein structure prediction· 1 Assay:proteomics· 1

Frequent Co-Authors

Ahmed M. AmaniD· 1 shared Andrea C. Uetrecht· 1 shared Antonio N. CalabreseiD· 1 shared Arindam DattaiD· 1 shared Ayesha SaleemiD· 1 shared Christine Misquitta· 1 shared Dahlia Kasimer· 1 shared Daniel N. Stein· 1 shared

Activity by Year

2019-2025 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 20 mutual co-author links

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1 shared paperBiochemistry

Ahmed M. AmanORCID

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2 papers

Recent·Most cited

BiochemistryNature Structural & Molecular BiologyPeer-reviewedMar 17, 2025

Molecular glues that inhibit deubiquitylase activity and inflammatory signalling

Francesca Chandler, Poli Adi Narayana Reddy, Smita Bhutda…·Elton Zeqiraj

The paper identifies first-in-class inhibitors (BLUEs) that selectively inhibit BRISC complex activity by stabilizing an autoinhibited dimer, reducing interferon-stimulated gene expression.

10 citations

experimental assaydrug response / drug discovery

𝕏 PostBluesky

Systems BiologybioRxivPreprintSep 16, 2019

Cell cycle regulation of mitochondrial protein import revealed by genome-scale pooled bimolecular fluorescence complementation screening

Kim Blakely, Patricia Mero, Roland R. Arnold…·Jason Moffat

The paper introduces MaGiCaL-BiFC, a method to identify protein-protein interactions in mammalian cells, and uses it to find novel interactions involving TOMM22, including a mitosis-specific interaction with CK2.

1 citation

humanproteomics

𝕏 PostBluesky