Ayesha Saleem

This study investigates plasma-derived extracellular vesicles as biomarkers for MELAS and their functional impact on mitochondrial respiration in skeletal muscle myotubes.

This study shows that breast milk extracellular vesicles from mothers with asthma differentially modulate cytokine release by airway smooth muscle cells depending on the donor and recipient cell type.

This study shows that exercise-induced extracellular vesicles reduce colon cancer cell viability and induce apoptosis, with higher intensity exercise producing stronger effects.

This study shows that ALA and DHA reduce oxidative phosphorylation and increase glycolysis in THP-1 monocytes, possibly via upregulation of PDK4.

This study surveys Canadian early-career health researchers to assess pandemic impacts, revealing high burnout rates and mental health declines.

This study shows that PI3K-dependent upregulation of hexokinase 2 (HK2) controls glucose metabolism and immune functions in B cells, with HK2-deficient B cells showing impaired metabolic and functional responses.

The paper identifies novel proteins and pathways in skeletal muscle-derived extracellular vesicles following chronic contractile activity, suggesting their role in metabolic and anti-tumorigenic effects.

This study shows that chronic contractile activity-induced skeletal muscle-derived extracellular vesicles reduce LLC cell viability and induce apoptosis and senescence.

The paper introduces MaGiCaL-BiFC, a method to identify protein-protein interactions in mammalian cells, and uses it to find novel interactions involving TOMM22, including a mitosis-specific interaction with CK2.