Author

Chiho Kim

The University of Texas Southwestern Medical CenterORCID 0000-0001-6846-5515Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

Click to filter author papers

Cancer Biology· 2

Signature Assays, Organisms & Methods

Click to filter · or open tag

Approach:experimental assay· 2 Organism:human· 2 Research Focus:cancer & tumor microenvironment· 1 Research Focus:host-pathogen & immune response· 1

Frequent Co-Authors

Yonghao YuiD· 2 shared Andrew S. LemoffiD· 1 shared Ann Marie FluschéiD· 1 shared Bingnan Wang· 1 shared Chuo CheniD· 1 shared Ilgen MenderiD· 1 shared Jerry W. ShayiD· 1 shared Lawrence LumiD· 1 shared

Activity by Year

2020-2025 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

Click any collaborator node to inspect or filter shared papers

Focal author (center)Selected co-authorORCID co-authorUnlinked name

Curved chords = mutual co-authorship

2 shared papersCancer Biology

Yonghao YuORCID

Mutual co-authors in cluster

Author profile →

2 papers

Recent·Most cited

Cancer BiologybioRxivPreprintSep 22, 2025

Targeting tankyrase scaffolding in the β-catenin destruction complex by PROTAC overcomes the limitation of catalytic inhibitors in cancer

Qian Wang, Liping Li, Lin You…·Chuo Chen

This study shows that degrading tankyrase (TNKS) with PROTACs overcomes the limitations of catalytic inhibitors by preventing AXIN puncta formation and enhancing WNT/β-catenin pathway suppression in colorectal cancer.

1 citation

humanexperimental assay

𝕏 PostBluesky

Cancer BiologyeLifePeer-reviewedAug 26, 2020

PARP1 inhibitors trigger innate immunity via PARP1 trapping-induced DNA damage response

Chiho Kim, Xu-Dong Wang, Yonghao Yu

This study identifies PARP1 trapping as the key mechanism by which PARP inhibitors trigger innate immunity, while PARP1 degraders avoid this response.

DOI 10.7554/elife.60637

humanexperimental assay

𝕏 PostBluesky