Author

Robert Lindsay Medcalf

Monash UniversityORCID 0000-0001-6885-3892Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Organism:mouse· 3 Research Focus:drug response / drug discovery· 2 Research Focus:differential expression· 1 Research Focus:protein structure prediction· 1 Assay:proteomics· 1 Organism:rat· 1 Approach:statistical model· 1

Frequent Co-Authors

Harshal H. NandurkariD· 2 shared Abbey WillcoxiD· 1 shared Amardeep S. DhilloniD· 1 shared Amy Vuong· 1 shared Andrew N. ClarksoniD· 1 shared Anna-Lisa E. LawrenceiD· 1 shared Antoine DufouriD· 1 shared Ashfaqul HoqueiD· 1 shared

Activity by Year

2023-2024 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 19 mutual co-author links

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2 shared papersNeuroscience

Harshal H. NandurkarORCID

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3 papers

Recent·Most cited

NeurosciencebioRxivPreprintOct 11, 2024

Thrombolysis exacerbates cerebrovascular injury after ischemic stroke via a VEGF-B dependent effect on adipose lipolysis

Ingrid Nilsson, Enming Joseph Su, Linda Fredriksson…·Ulf Eriksson

This study shows that thrombolysis worsens cerebrovascular injury after ischemic stroke by increasing adipose lipolysis, which can be mitigated by VEGF-B antagonism.

4 citations

mouseexperimental assay

𝕏 PostBluesky

NeuroscienceJournal of Thrombosis and HaemostasisPeer-reviewedMay 14, 2024

Development of endothelial-targeted CD39 as a therapy for ischaemic stroke

Natasha Ting Lee, Ioanna Savvidou, Carly Selan…·Maithili Sashindranath

This paper develops an endothelial-targeted CD39 therapy for ischaemic stroke, showing reduced infarct size and improved BBB integrity when administered 3 hours post-ischaemia.

11 citations

mouseexperimental assay

𝕏 PostBluesky

NeuroscienceMolecular & Cellular ProteomicsPeer-reviewedApr 6, 2023

N-Terminomic Changes of Neurons During Excitotoxicity Reveal Proteolytic Events Associated with Synaptic Dysfunctions and Inform Potential Targets for Neuroprotection

S. Sadia Ameen, Nane Griem‐Krey, Antoine Dufour…·Heung‐Chin Cheng

The paper identifies proteolytic events in neurons during excitotoxicity using N-terminomics, revealing calpain-mediated cleavage of synaptic proteins and potential therapeutic targets for neuroprotection.

25 citations

ratmouse

𝕏 PostBluesky