Development of endothelial-targeted CD39 as a therapy for ischaemic stroke
Natasha Ting Lee, Ioanna Savvidou, Carly Selan, Ilaria Calvello, Amy Vuong, David K. Wright, Robert Brkljača, Abbey Willcox, Joanne SJ Chia, Xiaowei Wang, Karlheinz Peter, Simon Christopher Robson, Robert Lindsay Medcalf, Harshal H. Nandurkar, Maithili Sashindranath
This paper develops an endothelial-targeted CD39 therapy for ischaemic stroke, showing reduced infarct size and improved BBB integrity when administered 3 hours post-ischaemia.
Journal of Thrombosis and Haemostasis · May 14, 2024Peer-reviewedNeuroscience