Béatrice Kunz

This study shows that CLIMP-63's luminal domain forms flexible trimers and its cytosolic tail mediates clustering, together determining ER sheet width.

This study identifies S-acylation-deacylation cycles as regulators of CMG2 biogenesis and function, showing APT2 inhibition can block anthrax toxin entry and Collagen VI degradation.

The paper identifies the Lipid Oxygen Radical Defense (LORD) pathway and shows it is epigenetically controlled, affecting oxidative stress and ferroptosis.

This study shows that ANTXR2 regulates COL6 turnover in skeletal muscle, and its deficiency leads to ECM stiffening and muscle dysfunction.

This study shows that CMG2 is essential for intestinal stem cell renewal after injury, as its loss impairs stem cell regeneration and Wnt signaling in mice.

This paper shows that ZDHHC6-mediated S-palmitoylation of CLIMP-63 regulates ER morphology by controlling its localization and abundance in mammalian cells.