Author

Paolo Bonaldo

University of PaduaORCID 0000-0002-9571-8140Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Organism:mouse· 3 Research Focus:cell type annotation· 2 Research Focus:differential expression· 2 Approach:experimental assay· 2 Research Focus:cancer & tumor microenvironment· 1 Research Focus:cell-cell communication· 1 Research Focus:development & morphogenesis· 1 Research Focus:gene regulatory network inference· 1

Frequent Co-Authors

Samuele MettiiD· 2 shared Adriana Figueroa GarciaiD· 1 shared Aurora De AcutisiD· 1 shared Béatrice KunziD· 1 shared Bert BlaauwiD· 1 shared Chantal FayadiD· 1 shared Chiara VillaiD· 1 shared Dimitrije MilunoviD· 1 shared

Activity by Year

2025-2026 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 16 mutual co-author links

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2 shared papersCell Biology

Samuele MettiORCID

Mutual co-authors in cluster

Author profile →

3 papers

Recent·Most cited

CD90 identifies distinct fractions of muscle stem cells with different modalities of activation and quiescence maintenance

Eyemen Kheir, Michela Libergoli, Serena Di Savino, Samuele Metti, Jonas Jensen, Jakob Wang, Niels Jessen, Francesca Murganti, Lorenzo Marramiero, M. Belicchi, Chiara Villa, Kristian Vissing, Mayank Verma, Lorenzo Giordani, Paolo Bonaldo, , Stefano Biressi

The paper identifies CD90 as a marker distinguishing two muscle stem cell subpopulations with different activation kinetics and quiescence maintenance mechanisms in mice and humans.

EMBO Reports · Nov 4, 2026Peer-reviewedCell Biology

Mitochondrial dysfunction plays a key role in premature musculoskeletal aging in hypochondroplasia mouse model

Chantal Fayad, Giulio Gatto, Stéphane Blouin, Michal Tamáš, Markus A. Hartmann, Dimitrije Milunov, Ida Chiara Guerrera, Soham Saha, Adriana Figueroa Garcia, Paolo Bonaldo, Frank Zaucke, Nadja Fratzl‐Zelman, Laurence Legeai‐Mallet

This study shows that mitochondrial dysfunction contributes to premature musculoskeletal aging in HCH mice, with proteomics revealing altered aging trajectories and bone fragility.

bioRxiv · Oct 22, 2026 · PreprintGenetics

Antxr2-mediated fine-tuning of Collagen VI ensures skeletal muscle function

Samuele Metti, Lucie Josepha Bracq, Matteo Signor, Nicola Facchinello, Lisa Gambarotto, Leonardo Nogara, Giulia Pigato, Laurence Abrami, Béatrice Kunz, Julien Duc, Patrizia Sabatelli, Aurora De Acutis, Gabriele Maria Fortunato, Giovanni Vozzi, Paola Braghetta, , Paolo Bonaldo

This study shows that ANTXR2 regulates COL6 turnover in skeletal muscle, and its deficiency leads to ECM stiffening and muscle dysfunction.

bioRxiv · Sep 11, 2025 · PreprintCell Biology