Author

Katherine A. Dalton

University of North Carolina at Chapel HillORCID 0000-0001-6934-3341Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Immunology· 1 Neuroscience· 1

Signature Assays, Organisms & Methods

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Organism:mouse· 2 Assay:CITE-seq· 1 Research Focus:differential expression· 1 Research Focus:drug response / drug discovery· 1 Research Focus:gene regulatory network inference· 1 Approach:genetic perturbation / CRISPR· 1 Approach:statistical model· 1 Assay:whole-genome sequencing· 1

Frequent Co-Authors

Aditi ChandraiD· 1 shared Alexander J. DimitriiD· 1 shared Alexander T. DilsiD· 1 shared Amy E. BaxteriD· 1 shared Benjamin D. PhilpotiD· 1 shared Bin GuiD· 1 shared Brian C. CooleyiD· 1 shared Bruce L. LevineiD· 1 shared

Activity by Year

2019-2024 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 24 mutual co-author links

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1 shared paperImmunology

Aditi ChandraORCID

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2 papers

Recent·Most cited

ImmunologyScience AdvancesPeer-reviewedNov 13, 2024

TET2 regulates early and late transitions in exhausted CD8+ T-cell differentiation and limits CAR T-cell function

Alexander J. Dimitri, Amy E. Baxter, Gregory M. Chen…·Joseph A. Fraietta

This study shows that targeting TET2 in CAR T-cells improves their anti-tumor responses by limiting terminal exhaustion and enhancing therapeutic potential.

42 citationstop 2%

mouseCITE-seq

𝕏 PostBluesky

NeurosciencebioRxivPreprintJul 15, 2019

Collaborative Cross Mouse Populations as a Resource for the Study of Epilepsy

Bin Gu, John R. Shorter, Lucy H. Williams…·Fernando Pardo‐Manuel de Villena

The paper uses Collaborative Cross mice to identify genetic loci and candidate genes associated with epilepsy traits, providing resources for studying seizure outcomes and developing new therapies.

DOI 10.1101/690917

mousewhole-genome sequencing

𝕏 PostBluesky