Koki Sakurai

This study identifies Nup153's role in repressing neuronal genes through HDAC1-mediated epigenetic regulation, influencing chromatin states and neuronal responsiveness.

This study shows that increased somatodendritic Tau interacts with nuclear envelope proteins, causing nuclear damage and altering gene expression related to AD and tauopathies.

This study shows that Importin α4 deficiency in mice leads to psychiatric-like behaviors and increased neuroinflammation, with elevated NF-κB and cytokine expression.

This study investigates sex-dependent effects of nicotine on discrimination learning and cognitive flexibility in mice, finding differential impacts on visual discrimination and reversal learning tasks.