Developmental BiologybioRxivPreprint
Extracellular matrix defects destabilise apical cytoarchitecture and mechanical properties during early Down syndrome neurodevelopment
Teresa P. Silva, Ekaterina R. Iijima, Ioakeim Ampartzidis…·Paula Alexandre
This study shows that ECM defects in Down syndrome neurodevelopment cause apical cytoarchitecture and mechanical property instability in neural stem cell models.
DOI 10.64898/2026.06.22.733824