Kun Tang

LUstiGE, Light responsive Ustilago maydis Gene Expression: Optogenetic control of morphogenesis and pathogenesis in the corn fungal pathogen Ustilago maydis

This study develops blue-light inducible gene expression switches to control morphogenesis and pathogenesis in Ustilago maydis, demonstrating their utility in regulating fungal invasion and tumor formation.

Red-light-only control of protein-protein interactions using a cyanobacteriochrome (UNICYCL)

This paper introduces a small red-light-responsive system for controlling protein-protein interactions using a cyanobacteriochrome, showing a >25-fold decrease in binding affinity under red light.

Green, orange, red, and far-red optogenetic tools derived from cyanobacteriochromes

The paper develops optogenetic tools that control protein-protein interactions using light in multiple colors by engineering binders for different states of cyanobacteriochromes.

Novel genetic loci affecting facial shape variation in humans

This study identifies 24 genetic loci associated with facial shape variation in humans through GWAS and confirms 13 of them in a multi-ethnic cohort.

Genome-wide Variants of Eurasian Facial Shape Differentiation and a prospective model of DNA based Face Prediction

The paper identifies six genome-wide significant loci associated with facial shape differences between Europeans and Han Chinese and develops a DNA-based 3D face prediction model.

A Chronological Atlas of Natural Selection in the Human Genome during the Past Half-million Years

This study estimates the timing of natural selection in the human genome over the past half-million years, identifying selection events related to brain evolution and Alzheimer's disease pathways.