Kim Nasmyth

This study investigates the structural architecture of two SMC-kleisin complexes, revealing a folded conformation mediated by a dynamic coiled-coil discontinuity.

This study shows Scc2/4 maintains cohesin on chromosomes during G1 by blocking a Wapl-independent release mechanism, but is unnecessary during S phase for establishing cohesion.

The paper investigates the structural dynamics of cohesin rings and identifies four sub-compartments formed by different head configurations during ATP binding and hydrolysis.

The paper investigates how cohesin organizes DNA through both topological and non-topological mechanisms, showing that hinge domain mutations affect DNA entrapment and loading.