Author

Johanna C. Scheinost

University of Oxford

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Molecular Biology· 3

Signature Assays, Organisms & Methods

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Approach:experimental assay· 3

Frequent Co-Authors

Kim NasmythiD· 3 shared Bin HuiD· 2 shared James CollieriD· 2 shared Madhusudhan SrinivasaniD· 2 shared Menelaos Voulgaris· 2 shared Naomi J PetelaiD· 2 shared Alexander Kurze· 1 shared Christophe ChapardiD· 1 shared

Activity by Year

2018-2019 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 35 mutual co-author links

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3 shared papersMolecular Biology

Kim NasmythORCID

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3 papers

Recent·Most cited

Scc2 counteracts a Wapl-independent mechanism that releases cohesin from chromosomes during G1 but is unnecessary during S phase for establishing cohesion

Madhusudhan Srinivasan, Naomi J Petela, Johanna C. Scheinost, James Collier, Menelaos Voulgaris, Maurici Brunet Roig, Frédéric Beckouët, Bin Hu, Kim Nasmyth

This study shows Scc2/4 maintains cohesin on chromosomes during G1 by blocking a Wapl-independent release mechanism, but is unnecessary during S phase for establishing cohesion.

bioRxiv · Jan 9, 2019 · PreprintMolecular Biology

The topology of DNA entrapment by cohesin rings.

Christophe Chapard, Robert Jones, Till van Oepen, Johanna C. Scheinost, Kim Nasmyth

The paper investigates the structural dynamics of cohesin rings and identifies four sub-compartments formed by different head configurations during ATP binding and hydrolysis.

bioRxiv · Dec 13, 2018 · PreprintMolecular Biology

The cohesin ring uses its hinge to organize DNA using non-topological as well as topological mechanisms

Madhusudhan Srinivasan, Johanna C. Scheinost, Naomi J Petela, Thomas G. Gligoris, Maria F. Wissler, Sugako Ogushi, James Collier, Menelaos Voulgaris, Alexander Kurze, Kok‐Lung Chan, Bin Hu, Vincenzo Costanzo, Kim Nasmyth

The paper investigates how cohesin organizes DNA through both topological and non-topological mechanisms, showing that hinge domain mutations affect DNA entrapment and loading.

Cell · May 1, 2018Peer-reviewedMolecular Biology