Clelia Peano

This paper identifies three glioblastoma stem cell morphoclasses using CellShape-seq, showing distinct functions and therapeutic vulnerabilities.

This study examines the epigenetic evolution of colorectal cancer and its microenvironment, identifying new therapeutic targets through single-cell analysis and functional validation.

This study identifies distinct gene regulatory networks driving naive and memory B cell differentiation, showing IRF4's role in both GC and plasma cell development independently of PRDM1.

The paper identifies transcriptionally distinct morphotypes of human basal radial glia and links their morphology, gene expression, and cell fate.

This study shows that early ASO treatment rescues developmental defects in SMA organoids by restoring SMN levels and correcting splicing defects.

This study characterizes the transcriptional and epigenetic profiles of hiPSC-NSCs and evaluates their safety in vivo, showing they resemble fetal NSCs and are safe for transplantation.

The paper shows that transient maternal IL-6 elevation during early neurodevelopment disrupts hippocampal connectivity and enhances glutamatergic synapses in offspring through the STAT3/RGS4 pathway.