Author

Genni Desiato

Institute of Genetic and Biomedical ResearchORCID 0000-0001-5281-0097Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Neuroscience· 3

Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Organism:mouse· 3 Research Focus:cell type annotation· 1 Research Focus:cell-cell communication· 1 Research Focus:differential expression· 1 Research Focus:gene regulatory network inference· 1 Approach:statistical model· 1

Frequent Co-Authors

Davide PozziiD· 3 shared Filippo MirabellaiD· 2 shared Alberto TermaniniiD· 1 shared Ari WaismaniD· 1 shared Carsten SchelmbaueriD· 1 shared Christina GrimmiD· 1 shared Clara A. Amegandjin· 1 shared Clelia PeanoiD· 1 shared

Activity by Year

2020-2024 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 23 mutual co-author links

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3 shared papersNeuroscience

Davide PozziORCID

Mutual co-authors in cluster

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3 papers

Recent·Most cited

NeuroscienceMolecular PsychiatryPeer-reviewedOct 9, 2024

Embryo-restricted responses to maternal IL-17A promote neurodevelopmental disorders in mouse offspring

David Andruszewski, David C. Uhlfelder, Genni Desiato…·Ilgiz A. Mufazalov

This study establishes a novel mouse model of prenatal IL-17A imprinting, showing embryo-restricted responses lead to behavioral deficits in offspring.

11 citations

mouseexperimental assay

𝕏 PostBluesky

NeuroscienceEMBO Molecular MedicinePeer-reviewedMar 5, 2021

The enhancement of activity rescues the establishment of Mecp2 null neuronal phenotypes

Linda Scaramuzza, Giuseppina De Rocco, Genni Desiato…·Nicoletta Landsberger

This study shows that enhancing neuronal activity rescues developmental defects in Mecp2 null neurons, improving their maturation and extending lifespan in a mouse model of Rett syndrome.

22 citations

mouseexperimental assay

𝕏 PostBluesky

NeurosciencebioRxivPreprintNov 2, 2020

Transient Maternal IL-6 boosts glutamatergic synapses and disrupts hippocampal connectivity in the offspring

Filippo Mirabella, Genni Desiato, Sara Mancinelli…·Davide Pozzi

The paper shows that transient maternal IL-6 elevation during early neurodevelopment disrupts hippocampal connectivity and enhances glutamatergic synapses in offspring through the STAT3/RGS4 pathway.

3 citations

mousestatistical model

𝕏 PostBluesky