Author

Xavier Renaudin

Université Paris CitéORCID 0000-0002-2970-6010Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Research Focus:cell signaling & trafficking· 2 Approach:experimental assay· 2 Organism:human· 2 Approach:biophysical modeling· 1 Assay:bulk RNA-seq· 1 Research Focus:cancer & tumor microenvironment· 1 Assay:DNA methylation· 1 Research Focus:drug response / drug discovery· 1

Frequent Co-Authors

Anna CampalansiD· 2 shared Alexander Myhr Skjetne· 1 shared Anders Knoph Berg-Eriksen· 1 shared Ane Marit WågbøiD· 1 shared Annikka Polster· 1 shared Capucine Siberchicot· 1 shared Chantal DesmazeiD· 1 shared Francisco José Naranjo-GalindoiD· 1 shared

Activity by Year

2025-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 25 mutual co-author links

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2 shared papersCell Biology

Anna CampalansORCID

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2 papers

Recent·Most cited

Functional Impact of Nth-like DNA glycosylase on Mitochondrial Dynamics

Lisa Hubers, Alexander Myhr Skjetne, Luisa Luna, Yohan Lefol, Solveig Osnes Lund, Ane Marit Wågbø, Xavier Renaudin, Annikka Polster, Zoe J da Silva, Anders Knoph Berg-Eriksen, Francisco José Naranjo-Galindo, Anna Campalans, Torkild Visnes, Hilde Loge Nilsen, Nicola Pietro Montaldo

This study shows that NTHL1 loss increases mtDNA copy number and mitochondrial function, enhancing cellular resilience to oxidative stress through stress response pathways.

Nucleic Acids Research · Sep 4, 2026Peer-reviewedCell Biology

G-quadruplex ligand RHPS4 compromises cellular radio-resistance by blocking the increase in mitochondrial mass and activity induced by ionising irradiation.

Sabine Tricot, Capucine Siberchicot, Isaline Bontemps, Chantal Desmaze, Gueorgui Kratassiouk, Marie Vandamme, Guillaume Pinna, Ivan Nemazanyy, Juan Pablo Radicella, Guy Lenaers, Xavier Renaudin, Jérome Lebeau, Anna Campalans

This study shows that the G-quadruplex ligand RHPS4 reduces radioresistance by inhibiting mitochondrial adaptations caused by ionising irradiation.

NAR Cancer · Sep 11, 2025Peer-reviewedCell Biology