Juan Pablo Radicella

The paper identifies a missing component of the ComB T4SS in H. pylori essential for DNA uptake, showing it is a hexameric ATPase interacting with ComB4.

This study identifies a tripartite protein complex essential for ssDNA uptake during natural transformation in firmicutes, validated through structural modeling and experimental assays.

This study shows that the G-quadruplex ligand RHPS4 reduces radioresistance by inhibiting mitochondrial adaptations caused by ionising irradiation.

This study identifies a protein-protein interaction between ComM and DprA that is critical for DprA to recruit ComM to promote recombination during natural transformation in Gram-negative bacteria.

This study shows that fetal exposure to BPA analogs causes DNA oxidation, leading to meiotic defects and oocyte aneuploidy in mice.

MasterPATH analyzes functional genomics screening data using network analysis to identify active molecular pathways associated with specific phenotypes.