Sylvain Martineau

This study identifies a non-metabolic role for hexokinase 2 as an RNA-binding protein that regulates SOX10 mRNA translation in melanoma, independent of its glycolytic activity.

This study shows 53BP1 interacts with RNA primers from Okazaki fragments during DNA replication, supporting their processing and highlighting an RNA-protein interaction at replication forks.

The paper shows that intronic polyadenylation (IPA) of MET affects tumour progression and therapy resistance by producing a short MET isoform that reduces invasiveness and enhances response to MAPK-targeted therapy.