Molecular BiologyScientific ReportsPeer-reviewed
Small molecule activation of metabolic enzyme pyruvate kinase muscle isozyme 2, PKM2, provides photoreceptor neuroprotection
Thomas J. Wubben, Mercy D. Pawar, Eric Weh…·Cagri G. Besirli
This study shows that activating PKM2 with ML-265 protects photoreceptors from stress-induced apoptosis in vitro and in vivo.
42 citations