Author

Mercy D. Pawar

University of Michigan

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Molecular Biology· 1 Neuroscience· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Assay:bulk RNA-seq· 1 Research Focus:cell type annotation· 1 Research Focus:cell-cell communication· 1 Research Focus:differential expression· 1 Research Focus:drug response / drug discovery· 1 Research Focus:gene regulatory network inference· 1 Organism:mouse· 1

Frequent Co-Authors

Andrew J. H. SmithiD· 2 shared Cagri G. BesirliiD· 2 shared Eric Weh· 2 shared Heather M. Hager· 2 shared Thomas J. WubbeniD· 2 shared Costas Andreas LyssiotisiD· 1 shared Li ZhangiD· 1 shared Lipeng Dai· 1 shared

Activity by Year

2020-2020 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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2 shared papersNeuroscience

Andrew J. H. SmithORCID

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2 papers

Recent·Most cited

Hexokinase 2 is dispensable for photoreceptor development but is required for survival during aging and outer retinal stress

Eric Weh, Zuzanna Lutrzykowska, Andrew J. H. Smith, Heather M. Hager, Mercy D. Pawar, Thomas J. Wubben, Cagri G. Besirli

This study shows that HK2 is not needed for photoreceptor development but is essential for their survival during aging and stress, with its non-enzymatic role in AKT signaling being critical.

Cell Death and Disease · Jun 4, 2020Peer-reviewedNeuroscience

Small molecule activation of metabolic enzyme pyruvate kinase muscle isozyme 2, PKM2, provides photoreceptor neuroprotection

Thomas J. Wubben, Mercy D. Pawar, Eric Weh, Andrew J. H. Smith, Peter Sajjakulnukit, Li Zhang, Lipeng Dai, Heather M. Hager, Manjunath P. Pai, Costas Andreas Lyssiotis, Cagri G. Besirli

This study shows that activating PKM2 with ML-265 protects photoreceptors from stress-induced apoptosis in vitro and in vivo.

Scientific Reports · Feb 19, 2020Peer-reviewedMolecular Biology