Idoia Quintana Urzainqui

The 16p11.2 microdeletion enhances gene expression variability between human IPSC derived forebrain interneuron progenitor cells in culture.

This study finds that the 16p11.2 microdeletion increases transcript level variation in human iPSC-derived forebrain interneuron progenitors, affecting gene regulation and potentially contributing to neurodevelopmental and metabolic phenotypes.

An atlas of shark developing telencephalon reveals ancient origin of basal progenitors and Cajal-Retzius cells

This study uses single-cell and spatial transcriptomics to analyze shark telencephalon development, revealing ancient origins of basal progenitors and Cajal-Retzius cells in gnathostomes.

Pax6 loss alters the morphological and electrophysiological development of mouse prethalamic neurons

This study shows that Pax6 loss affects neurite extension, axon initial segment properties, and electrophysiological function in developing mouse prethalamic neurons.

Identifying developing interneurons as a potential target for multiple genetic autism risk factors in human and rodent forebrain.

The paper identifies developing interneurons as a potential target for autism genetic risk factors by analyzing human and rodent neural data.

The role of the diencephalon in the guidance of thalamocortical axons in mice

This study investigates the role of the diencephalon in guiding thalamocortical axons in mice, finding that molecular cues in the thalamus are critical for proper topographic mapping.

Tissue-specific actions of Pax6 on proliferation-differentiation balance in the developing forebrain are Foxg1-dependent

The paper shows Pax6 has opposite effects on proliferation-differentiation balance in murine diencephalon and cortex, with Foxg1 mediating these differences.