Kwanha Yu

This study identifies elongin B as a key regulator of Pol2 elongation in H3K27M-mutant diffuse midline glioma, showing its role in maintaining chromatin and transcriptional dysregulation.

This study shows that combining CDK9 inhibitors with neuropsychiatric drugs reduces diffuse midline glioma growth by altering H3 dopaminylation and CaMKII signaling.

This study identifies specific developmental epigenomic states that enable ZFTA-RELA-driven ependymoma formation and reveals how these states shape tumor progression.

This study investigates EZHIP mutations in pediatric brain tumors, showing their presence in new tumor types and revealing their role in neuronal-like gene programs and polyamine metabolism repression.

This study identifies a neurovascular progenitor cell type in glioblastoma that links distinct malignant lineages and influences tumor composition and survival.