Chartsiam Tipgomut

This study identifies lipid-laden macrophages as an immunosuppressive niche in PCNSL, validated through spatial transcriptomics and mouse models, and shows SYK inhibition reverses their tumor-supportive activity.

PatternExtract generates spatial point patterns from pathology images and cell coordinates using a two-kernel segmentation method and automated classification, validated on lymphoma data.

This study maps ribosomal protein (RP) gene expression across human tissues using single-cell RNA sequencing, revealing tissue-specific patterns and linking RP heterogeneity to reproductive health and anaemia.