Author

Filip Roudnicky

F. Hoffmann-La Roche AGORCID 0000-0001-7156-2383Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Research Focus:gene regulatory network inference· 3 Organism:human· 3 Research Focus:cell type annotation· 2 Approach:experimental assay· 2 Research Focus:cell signaling & trafficking· 1 Assay:CRISPR screen· 1 Research Focus:differential expression· 1 Research Focus:drug response / drug discovery· 1

Frequent Co-Authors

Anne Sofie G. LarseniD· 1 shared Anne SpangiD· 1 shared Arianna Mei· 1 shared Benjamin HaleyiD· 1 shared Carolina Hager· 1 shared Charles PlessyiD· 1 shared Christian WeileiD· 1 shared Christoph PatschiD· 1 shared

Activity by Year

2019-2025 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 17 mutual co-author links

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1 shared paperNeuroscience

Anne Sofie G. LarsenORCID

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3 papers

Recent·Most cited

Cell BiologyNature CommunicationsPeer-reviewedJun 30, 2025

A CRISPR/Cas9 screen reveals proteins at the endosome-Golgi interface that modulate cellular ASO activity

Liza Malong, Jessica Roskosch, Carolina Hager…·Filip Roudnicky

The paper uses a CRISPR/Cas9 screen to identify genes modulating ASO activity, revealing AP1M1 and TBC1D23 as key regulators of endosome-Golgi transport affecting ASO efficacy.

9 citations

humangenetic perturbation / CRISPR

𝕏 PostBluesky

NeurosciencebioRxivPreprintMar 16, 2024

An arrayed CRISPR/Cas9 screen identifies mTORC1 as a regulator of lipid droplet accumulation in APOE E3 and APOE KO iPSC-derived microglia

Sonja Meier, Anne Sofie G. Larsen, Florian Wanke…·Ravi Jagasia

DOI 10.1101/2024.03.16.585330

humanCRISPR screen

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NeurosciencebioRxivPreprintApr 5, 2019

Decoding neuronal diversity by single-cell Convert-seq

Joachim Luginbühl, Tsukasa Kouno, Rei Nakano…·Jay W. Shin

This study introduces Convert-seq, a method combining scRNA-seq and ectopic gene expression to identify gene regulatory networks during cell reprogramming.

3 citations

humanscRNA-seq

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