Author

Dario Rizzotto

Austrian Academy of SciencesORCID 0000-0003-0106-7496Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

Click to filter author papers

Molecular Biology· 2 Cell Biology· 1 Developmental Biology· 1

Signature Assays, Organisms & Methods

Click to filter · or open tag

Organism:human· 3 Approach:statistical model· 3 Assay:bulk RNA-seq· 2 Research Focus:differential expression· 2 Approach:experimental assay· 2 Research Focus:gene regulatory network inference· 2 Research Focus:cell type annotation· 1 Research Focus:host-pathogen & immune response· 1

Frequent Co-Authors

Alberto IngaiD· 2 shared Andreas VillungeriD· 2 shared Annalisa RossiiD· 2 shared Erik DassiiD· 2 shared Etienne D. JacototiD· 2 shared Ahwan PandeyiD· 1 shared Alessandra BisioiD· 1 shared Alessandro QuattroneiD· 1 shared

Activity by Year

2020-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 20 mutual co-author links

Click any collaborator node to inspect or filter shared papers

Focal author (center)Selected co-authorORCID co-authorUnlinked name

Curved chords = mutual co-authorship

2 shared papersMolecular Biology

Alberto IngaORCID

Mutual co-authors in cluster

Author profile →

4 papers

Recent·Most cited

Developmental BiologyCell Death and DifferentiationPeer-reviewedJan 12, 2026

The PIDDosome controls cardiomyocyte polyploidization during postnatal heart development

Marina Leone, Nadine Kinz, Felix Eichin…·Andreas Villunger

This study shows the PIDDosome restricts cardiomyocyte polyploidization during postnatal heart development through p21/Cdkn1a, independent of p53.

7 citationstop 2%

mousebulk RNA-seq

𝕏 PostBluesky

Cell BiologyScience AdvancesPeer-reviewedOct 30, 2024

Caspase-2 kills cells with extra centrosomes

Dario Rizzotto, Vincenza Vigorito, Patricia Rieder…·Luca L. Fava

The paper shows that caspase-2 triggers apoptosis in cells with extra centrosomes, preventing polyploidization through mitochondrial pathways.

21 citations

humanexperimental assay

𝕏 PostBluesky

Molecular BiologyCancersPeer-reviewedAug 31, 2021

The RNA helicase DHX30 coordinates cytoplasmic translation and mitochondrial function contributing to cancer cell survival

Bartolomeo Bosco, Annalisa Rossi, Dario Rizzotto…·Alberto Inga

This paper shows DHX30 coordinates cytoplasmic and mitochondrial translation, affecting cancer cell survival and prognosis through a 15-gene signature.

23 citations

humanbulk RNA-seq

𝕏 PostBluesky

Molecular BiologyCell ReportsPeer-reviewedMar 1, 2020

p53-induced apoptosis is specified by a translation program regulated by PCBP2 and DHX30.

Dario Rizzotto, Sara Zaccara, Annalisa Rossi…·Alberto Inga

This study identifies a translational control mechanism regulated by PCBP2 and DHX30 that determines the outcome of p53 activation by Nutlin, shifting the response from cell cycle arrest to apoptosis.

31 citations

humanstatistical model

𝕏 PostBluesky