Author

Matthew Bergstresser

Harvard UniversityORCID 0000-0001-7195-3595Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Neuroscience· 3

Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Organism:mouse· 3 Organism:human· 1

Frequent Co-Authors

Dylan V. NeeliD· 2 shared Georgia GunneriD· 2 shared Himanish BasuiD· 2 shared Isaac M. ChiuiD· 2 shared Aaron HeldiD· 1 shared Alice S. Chen‐PlotkiniD· 1 shared AnnaLin M. WooiD· 1 shared Brian J. WaingeriD· 1 shared

Activity by Year

2021-2025 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 36 mutual co-author links

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2 shared papersNeuroscience

Dylan V. NeelORCID

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3 papers

Recent·Most cited

NeuroscienceNeurobiology of DiseasePeer-reviewedAug 5, 2025

Gasdermin D is activated but does not drive neurodegeneration in SOD1G93A model of ALS: Implications for targeting pyroptosis

Georgia Gunner, Himanish Basu, Yong Lu…·Isaac M. Chiu

This study shows GSDMD is activated in ALS mice but its loss does not improve disease outcomes or reduce neuroinflammation.

9 citationstop 3%

mouseexperimental assay

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NeuroscienceNeuronPeer-reviewedMar 13, 2023

Gasdermin-E mediates mitochondrial damage in axons and neurodegeneration

Dylan V. Neel, Himanish Basu, Georgia Gunner…·Isaac M. Chiu

This study identifies GSDME as a mediator of mitochondrial damage and axon loss in neurodegenerative diseases, showing its role in ALS and FTD models.

139 citationstop 1%

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NeurosciencebioRxivPreprintMay 8, 2021

Astrocyte plasticity ensures continued endfoot coverage of cerebral blood vessels and integrity of the blood brain barrier, with plasticity declining with normal aging.

William A. Mills, Shan Jiang, Joelle Martin…·Harald W. Sontheimer

This study shows astrocyte plasticity maintains vascular coverage and BBB integrity by replacing ablated astrocytes, but this plasticity declines with aging.

3 citations

mouseexperimental assay

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