Xuedong Liu

This study identifies PRDX6 as a modulator of resistance to HDAC inhibitors and immune checkpoint therapies by suppressing ferroptosis and enhancing T-cell infiltration.

This study shows largazole suppresses superenhancer accessibility by inhibiting SP1 and BRD4, leading to mitotic chromosome misalignment and cell cycle arrest.

The paper shows that TGF-β signaling responses are determined by the receptor with the lowest abundance, following Liebig's law of the minimum, across cell types and single cells.

This study shows CBD disrupts cholesterol homeostasis in human cell lines, altering metabolites, transcripts, and proteins related to cholesterol biosynthesis, transport, and storage.