Frank J. Dekker

The paper shows that fasting disrupts the TGF-β-InsP6-HDAC3 axis, inducing ER stress and eliminating DNA-damaged cells to maintain tissue quality.

This study identifies MIF as a key immunosuppressive factor in neuroblastoma that inhibits CAR T-cell efficacy, showing that blocking MIF enhances T-cell activation and therapeutic potential.

The paper investigates chromatin protein deposition bias at G-quadruplex sites, finding a reciprocal association of parental and new proteins with G4 and C4 DNA strands, respectively.

This study shows that inhibiting SmLSD1 with MC3935 causes transcriptional changes and structural damage in Schistosoma mansoni, leading to parasite death.

The paper shows that inhibiting HDAC1 and HDAC2 improves CRISPR/Cas9 gene editing efficiency by opening chromatin and enhancing Cas9 access.