Author

Laura C. Van Eyndhoven

University of PennsylvaniaORCID 0000-0001-7230-1134Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Bioengineering· 1 Immunology· 1 Systems Biology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Organism:human· 2 Assay:ATAC-seq· 1 Assay:bulk RNA-seq· 1 Research Focus:cell type annotation· 1 Research Focus:differential expression· 1 Research Focus:host-pathogen & immune response· 1 Assay:proteomics· 1

Frequent Co-Authors

Aoife O’FarrelliD· 2 shared Arjun RajiD· 2 shared Abhyudai SinghiD· 1 shared Apurv SrivastaviD· 1 shared Catherine G. TriandafillouiD· 1 shared Grant KinsleriD· 1 shared Haowen YangiD· 1 shared Ileana M. CristeaiD· 1 shared

Activity by Year

2023-2025 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 30 mutual co-author links

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2 shared papersBioengineering

Aoife O’FarrellORCID

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3 papers

Recent·Most cited

BioengineeringbioRxivPreprintJun 27, 2025

Lineage memory shapes viral resistance barriers in human skin

Laura C. Van Eyndhoven, Grant Kinsler, Jingchao Zhang…·Arjun Raj

The paper shows that viral resistance in human skin cells is inherited through cellular lineages and preserved across generations.

2 citations

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ImmunologybioRxivPreprintJan 22, 2025

Innate Immune Memory is Stimulus Specific

Aoife O’Farrell, Zijian Niu, Jingxin Li…·Arjun Raj

This study shows that innate immune memory in macrophages is stimulus-specific, with distinct phenotypic and epigenetic responses depending on the initial training stimulus.

5 citations

humanbulk RNA-seq

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Systems BiologybioRxivPreprintMar 27, 2023

Temporal perturbation of STAT1/2 activity reveals dynamic ligand discrimination of type I interferon signaling

Haowen Yang, Thomas van de Kreeke, Laura C. Van Eyndhoven, Jurjen Tel

The paper investigates how STAT1/2 activity differs in response to IFN and IFNβ through temporal perturbation, revealing distinct signaling dynamics and refractory states.

DOI 10.1101/2023.03.27.534340

experimental assay

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