Author
Vanderbilt UniversityORCID 0000-0001-7257-3674Unclaimed ORCID profile · follow to get notified of new preprints
7 papers
Recent·Most cited
Juan Carvajal-Garcia, Houra Merrikh
The paper identifies AddA and AddB as essential factors for resolving head-on replication-transcription conflicts in Bacillus subtilis by unwinding reversed replication forks.
Oyku Sensoy, Juan Carvajal-Garcia, Joshua R. Heyza…·Houra Merrikh
The paper identifies a conserved mechanism preventing replication restart from RNA:DNA hybrids in bacteria and mammals.
Oyku Sensoy, Juan Carvajal-Garcia, Shahin Boumi, Houra Merrikh
The paper shows that PNPase degrades RNA in R-loops to prevent replication restart and reduce mutations during replication-transcription conflicts.
Juan Carvajal-Garcia, Ariana Nakta Samadpour, Angel J Hernandez Viera, Houra Merrikh
The paper shows that endogenous oxidative stress drives mutagenesis in bacteria through transcription-coupled repair, contributing to antibiotic resistance evolution.
Juan Carvajal-Garcia, K. Nicole Crown, Dale A. Ramsden, Jeff J. Sekelsky
This paper shows that DNA polymerase theta compensates for the loss of Holliday junction resolvases by suppressing mitotic crossing over and maintaining genomic stability.
Juan Carvajal-Garcia, Jang-Eun Cho, Pablo Carvajal-Garcia…·Dale A. Ramsden
This study elucidates how DNA Polymerase Theta identifies microhomologies during repair and shows how this process leads to genomic scars in cancer.
Juan Carvajal-Garcia, Evan R. Gales, Dale A. Ramsden, Jeff J. Sekelsky
The paper identifies Mus302 as the Drosophila ortholog of RFWD3 and shows it does not function in DNA repair like its human counterpart.