Author

Noah W. Palm

Yale UniversityORCID 0000-0001-7262-9455Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Research Focus:cell type annotation· 3 Approach:experimental assay· 3 Organism:human· 3 Research Focus:host-pathogen & immune response· 2 Organism:mouse· 2 Assay:proteomics· 2 Research Focus:clustering· 1 Assay:metagenomics· 1

Frequent Co-Authors

Nicole D. SonnertiD· 2 shared Aaron M. RingiD· 1 shared Allen C. SteereiD· 1 shared Catherine Leimkuhler GrimesiD· 1 shared Christine JacobsiD· 1 shared Deguang Song· 1 shared Dejiang WangiD· 1 shared Di Zhang· 1 shared

Activity by Year

2025-2026 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 14 mutual co-author links

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2 shared papersMicrobiology

Nicole D. SonnertORCID

Mutual co-authors in cluster

Author profile →

4 papers

Recent·Most cited

Spatially resolved host-fungal transcriptomics profiling by fungal-DBiT

Xiaohui Yu, Fu Qiang Gao, Deguang Song, Gaocai Li, Dejiang Wang, Shenjie Wang, Xiangjun Di, Shujie He, Liyun Lin, Junyi Xu, Di Zhang, Yu Jin, Jing Du, Noah W. Palm, Liu Yang

This study introduces fungal-DBiT, a spatial transcriptomic platform that maps host and fungal RNAs in tissue sections, revealing spatial heterogeneity in fungal localization and host responses during infection and under physiological conditions.

bioRxiv · Oct 19, 2026 · PreprintMicrobiology

Helicobacter pylori allelic variation in cell surface genes influences human exoproteome binding and stomach tissue adherence

Jacob P. Frick, Nicole D. Sonnert, Jazmine A. Snow, Moira Overly, Hyojik Yang, Megan N Stoppler, Aaron M. Ring, Robert K. Ernst, Noah W. Palm, Nina R. Salama

This study identifies allelic variation in H. pylori cell surface genes that influence exoproteome binding and gastric tissue adherence through structural changes in lipopolysaccharide.

bioRxiv · Mar 6, 2026 · PreprintMicrobiology

Children Who Develop Celiac Disease Exhibit Distinct Metabolic Pathways Among Their Gut Microbiota Years Before Diagnosis

Kristina Kelley, Dogus Dogru, Qian Huang, Yi Yang, Noah W. Palm, Johnny Ludvigsson

Microbiology Spectrum · Feb 4, 2025Peer-reviewedMicrobiology

Bacterial and host enzymes modulate the inflammatory response produced by the peptidoglycan of the Lyme disease agent

Joshua W. McCausland, Zachary A. Kloos, Irnov Irnov, Nicole D. Sonnert, Junhui Zhou, Rachel Putnik, Elizabeth A. Mueller, Allen C. Steere, Noah W. Palm, Catherine Leimkuhler Grimes, Christine Jacobs

This study identifies bacterial enzymes that modify peptidoglycan fragments from Borrelia burgdorferi, showing they are poor immune stimulators and that host enzymes like PGLYRP2 are less active in joint fluids, contributing to persistent arthritis.

bioRxiv · Jan 8, 2025 · PreprintMicrobiology